A short, efficient synthesis of an anthracycline antitumor antibiotic synthon
β Scribed by Jose Alexander; L.A. Mitscher
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 189 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
Synthetic approaches to the anthracyclines related to adriamycin-daunomytin are of great interest because of the relative costliness of the agents and their useful clinical properties against a relatively broad spectrum of tumors?
Of the presently available syntheses, those based upon the Diels-Alder pathways
π SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
The asymmetric synthesis of the A-ring of 1Ξ±,25-dihydroxyvitamin D 3 , (Z)-2, from 5-tert-butyldimethylsiloxy-2-cyclohexenone [(S)-1], is described where an intramolecular lactonization using cat. scandium triflate is the key reaction.