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Regiospecific synthesis of linear quinone systems: efficient convergent synthesis of anthracycline intermediates

✍ Scribed by Kathlyn A. Parker; James L. Kallmerten

Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
236 KB
Volume
20
Category
Article
ISSN
0040-4039

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✦ Synopsis

The antineoplastic activity and challenging structural features of the anthracycline antibiotics have caused extensive efforts to be directed toward their chemical synthesis. 2 In particular, Adriamycin (la) and daunomycin (lb) have become the focus of much attention.

excellent contributions in this area, regiospecific syntheses of the aglycones L3 2b,3a,4

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