✦ LIBER ✦
Stereo- and regiospecific allylation of 4-chloroazetidinones with allylsilanes: Convergent synthesis of a key intermediate for (+)-thienamycin
✍ Scribed by Matsuhiko Aratani; Kozo Sawada; Masashi Hashimoto
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 270 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
An efflclent stereospeclflc synthesis of optIcally active 4-allylazetldlnones (6_, 7_, z, and 15a,b) has been accomplished using sliver-promoted coupling reaction of allylsllanes (2 and 14b) wzth 4-chloroazetldlnones (3, 4, and lOa,b) derived from penlcllllns.