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Application of SIMPLISMA for the assessment of peak purity in liquid chromatography with diode array detection

✍ Scribed by F.Cuesta Sánchez; D.L. Massart

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
836 KB
Volume
298
Category
Article
ISSN
0003-2670

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✦ Synopsis

The application of SIMPLISMA for the investigation of peak purity with liquid chromatography and diode array detection (LC-DAD) is proposed. SIMPLISMA is applied in the chromatographic direction, and is used to detect pure zones in the chromatogram. The performance of SIMPLISMA and of an approach based on the Gram-Schmidt orthogonalization technique are compared.

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