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Algorithms for the assessment of peak purity in liquid chromatography with photodiode-array detection. Part II

✍ Scribed by F. Cuesta Sánchez; M.S. Khots; D.L. Massart

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
671 KB
Volume
290
Category
Article
ISSN
0003-2670

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✦ Synopsis

Ahstraet

Two modifications of the algorithm based on the Gram-Schmidt orthogonalization technique for the assessment of peak purity are presented. The performance of this approach is investigated for liquid chromatography with photodiode-array detection (LC-DAD) data, although its applicability is not restricted to this experimental model. This method is applied to simulated and experimental data where two compounds are eluting, but can be applied when more compounds are eluting. The results are compared with the ones obtained previously with the first version of this algorithm.

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