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Antimalarial activities of gedunin and 7-methoxygedunin and synergistic activity with dillapiol

✍ Scribed by S OMAR; K GODARD; A INGHAM; H HUSSAIN; V WONGPANICH; J PEZZUTO; T DURST; C EKLU; M GBEASSOR; P SANCHEZ-VINDAS; L POVEDA; B J R PHILOGENE; J T ARNASON


Book ID
111327646
Publisher
Association of Applied Biologists
Year
2003
Tongue
English
Weight
182 KB
Volume
143
Category
Article
ISSN
0003-4746

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## Abstract magnified image Computer modelling suggests that 7‐benzylamino‐1‐isoquinolinamines should mediate antimalarial effects by a mechanism distinct from that employed by existing antimalarial drugs. A series of these compounds was prepared in seven synthetic steps, via reductive amination o