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Synthesis and Antimalarial Activity of 7-Benzylamino-1-isoquinolinamines.

✍ Scribed by Clare E. Gutteridge; Marshall M. Hoffman; Apurba K. Bhattacharjee; Lucia Gerena

Book ID
102005191
Publisher
John Wiley and Sons
Year
2007
Weight
14 KB
Volume
38
Category
Article
ISSN
0931-7597

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Synthesis and antimalarial activity of 7
Synthesis and antimalarial activity of 7-benzylamino-1-isoquinolinamines
✍ Clare E. Gutteridge; Marshall M. Hoffman; Apurba K. Bhattacharjee; Lucia Gerena πŸ“‚ Article πŸ“… 2007 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 309 KB

## Abstract magnified image Computer modelling suggests that 7‐benzylamino‐1‐isoquinolinamines should mediate antimalarial effects by a mechanism distinct from that employed by existing antimalarial drugs. A series of these compounds was prepared in seven synthetic steps, via reductive amination o