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Antifilarial and antimalarial agents. Basically substituted 10-aminobenzo[b] [1,5] naphthyridines, 10-Aminobenzo[b] [1,5] naphthyridine N-Oxides, and 8-Amino-1,5-naphthyridines

✍ Scribed by Edward F. Elslager; S. C. Perricone; Donald F. Worth

Book ID
112122161
Publisher
Journal of Heterocyclic Chemistry
Year
1970
Tongue
English
Weight
788 KB
Volume
7
Category
Article
ISSN
0022-152X

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πŸ“œ SIMILAR VOLUMES

Synthesis of substituted pyrimido[4,5-b]
Synthesis of substituted pyrimido[4,5-b] and [5,4-c]-[1,8]naphthyridines
✍ Christophe Plisson; Jacques Chenault πŸ“‚ Article πŸ“… 2001 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 56 KB

## Abstract Ethyl 1‐ethyl‐7‐methyl‐4‐oxo‐1,4‐dihydro[1,8]naphthyridine‐3‐carboxylate (**1**), precursor of nalidixic acid, has been converted in two steps through ([1,8]naphthyridin‐3‐yl)carbonylguanidine derivatives into substituted pyrimido[4,5‐__b__] and [5,4‐__c__][1,8]naphthyridines.

Synthesis of bridged analogs of epibatid
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✍ Lawrence E Brieaddy; S Wayne Mascarella; HernΓ‘n A Navarro; Robert N Atkinson; M. πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 86 KB

The synthesis of conformationally locked analogs of epibatidine are described in which the key step is an intramolecular reductive palladium-catalyzed Heck-type coupling.