The antidiarrhoeal potential of a methanol extract of the aerial parts of Jussiaea suffruticosa Linn. (MEJS) was studied with several experimental models of diarrhoea in rats. MEJS treated rats showed significant inhibitory activity against castor oil induced diarrhoea and PGE 2 induced enteropoolin
Antidiarrhoeal Activity of Hamelia patens Methanol Extract in Rats and Mice
✍ Scribed by Salud Pérez G.; Miguel A. Zavala S.; Rosario Vargas S.; Edgar Hernández Z.; Rosa M. Pérez G.
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 265 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-418X
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✦ Synopsis
The inhibitory action of Hamelia patens methanol extract was studied in vitro on uterus, ileum and duodenum, and the antidiarrhoeal activity was evaluated in vivo on mice and rats. It was found that for the uterus and intestine the inhibitory response was dose dependent and the major antidiarrhoeal effect was observed at a dose of 100 mgkg.
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