Annovel formamidine linker for use in solid-phase synthesis
โ Scribed by Paul S. Furth; Michael S. Reitman; Alan F. Cook
- Book ID
- 104257555
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 189 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. Ever-increasing numbers of ambitious solution phase reactions are being adapted for solid-phase organic chemistry and to accommodate them, large numbers of sophisticated linker units have been develope
Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. Ever-increasing numbers of ambitious solution phase reactions are being adapted for solid-phase organic chemistry and to accommodate them, large numbers of sophisticated linker units have been develope
A range of linkers for the important amidine pharmacophore, cleavable using acid or light have been developed for use in library synthesis. The utility of these linkers is demonstrated by the solid phase synthesis of the Novartis (ex-Ciha) phase II compound CGS-25019C.