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Animal cell culture in stirred bioreactors: observations on scale-up

✍ Scribed by Chisti, Yusuf


Book ID
122850522
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
645 KB
Volume
28
Category
Article
ISSN
1873-3298

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Animal cell culture in stirred bioreacto
✍ Y. Chisti πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 518 KB

Scale-up of stirred tank bioreactors from 0.02 m 3 to 0.3 m 3 commercial plant is discussed for hybridoma suspension culture. Schemes for dissolved oxygen control with sparged air in serum containing media are described as well as mechanical breakage of foam in small and large bioreactors. Porous me