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Angiographic response of locally advanced soft-tissue sarcoma following hyperthermic isolated limb perfusion with tumor necrosis factor

✍ Scribed by Annette F. T. Olieman; Robert J. van Ginkel; Harald J. Hoekstra; Eduard L. Mooyaart; Willemina M. Molenaar; Heimen Schraffordt Koops


Publisher
Springer
Year
1997
Tongue
English
Weight
967 KB
Volume
4
Category
Article
ISSN
1068-9265

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## Background and Objectives: The prognosis for recurrent multifocal limb soft tissue sarcoma (STS) is dismal due to systemic spread. However, many of these patients undergo amputation due to ineffective local control. The purpose of the present study was to determine whether isolated limb perfusi

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## Abstract ## BACKGROUND Since 1992, isolated limb perfusion (ILP) with tumor necrosis factor‐α (TNFΞ±) and melphalan has been used for the treatment of patients with unresectable soft tissue sarcomas of the extremities. The authors retrospectively studied the results of limb salvage surgery using