𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Analysis ofGADD45Asequence variations in French Canadian families with high risk of breast cancer

✍ Scribed by Sylvie Desjardins; Geneviève Ouellette; Yvan Labrie; Jacques Simard; INHERIT BRCAs; Francine Durocher

Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
263 KB
Volume
53
Category
Article
ISSN
1435-232X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Genetic variants and haplotype analyses
Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families
✍ Sylvie Desjardins; Pascal Belleau; Yvan Labrie; Geneviève Ouellette; Paul Besset 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 214 KB 👁 1 views

## Abstract Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes __BRCA1__ and __BRCA2__, found in about 25% of high‐risk families, as well as few other low penetrance genes such as __ATM__ and __CHEK2__. Approximately two‐thirds of the multiple cases fa

Analysis of RAD51C germline mutations in
Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients
✍ Ella R. Thompson; Samantha E. Boyle; Julie Johnson; Georgina L. Ryland; Sarah Sa 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB

There is strong evidence that overtly inactivating mutations in RAD51C predispose to hereditary breast and ovarian cancer but the prevalence of such mutations, and whether they are associated with a particular clinical phenotype, remains unclear. Resolving these questions has important implications