Confirmation of linkage and estimation of the proportion of families who are linked in large independent datasets is essential to understanding the significance of cancer susceptibility genes. We report here on an analysis of 150 highrisk prostate cancer families (2,176 individuals) for potential li
Linkage analysis of Dutch families at high risk for breast cancer
β Scribed by AF Wilson; JE Bailey-Wilson; FJ Cleton; RC Elston; MC King
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 308 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0741-0395
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We perfom both segregation and linkage analysis for an hypothesized breast cmxr suscqt&ility gene u d e r a s w l e analyze these families, we present a breast cancer penetrance model a sirrgle parameter for each gemtype. lmis is in corrtrast to previms models that require two or more parameters for
## Abstract Breast cancer is diagnosed in over one million women worldwide every year. Until breast cancer can be prevented, early detection offers the best chance for cure. Mammographic screening is an effective method for early detection in averageβrisk women. However, the sensitivity of mammogra