Analysis of the retinoblastoma gene in human endometrial carcinoma
β Scribed by Yuji Yaginuma; Hideto Katayama; Kiitirou Kawai; Julio Cesar Duenas; Mutsuo Ishikawa
- Book ID
- 116039318
- Publisher
- Lippincott Williams and Wilkins
- Year
- 1996
- Tongue
- English
- Weight
- 428 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0029-7844
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## Abstract The present study was undertaken to define the gene(s) of importance on the long arm of chromosome 18 (chromosome 18q) in endometrial carcinomas. We analyzed loss of heterozygosity (LOH) at 3 loci on chromosome 18q and DCC gene expression by the reverseβtranscriptase/polymerase chain re
## Abstract Although carcinoma of the uterine endometrium is the most frequently diagnosed malignancy of the female reproductive tract, the molecular genetic features of this tumor have yet to be described in significant detail. Since mutations of the __p53__ tumor suppressor gene are the single mo