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Absence of Retinoblastoma gene product in human primary oral cavity carcinoma

✍ Scribed by Z.P. Pavelic; M. Lasmar; LJ Pavelic; C. Sorensen; PJ Stambrook; N. Zimmermann; J.J Gluckman


Book ID
116169212
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
841 KB
Volume
32
Category
Article
ISSN
0964-1955

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## Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity, representing ˜90% of all oral carcinomas and accounting for 3–5% of all malignancies. The __WWOX__ gene (WW‐domain containing oxidoreductase) is a candidate tumor suppressor gene located at 16q