Analysis of the 5HT-2A T102C receptor polymorphism and psychotic symptoms in Alzheimer's disease
β Scribed by David Craig; Caroline Donnelly; Dominic Hart; Robyn Carson; Peter Passmore
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 53 KB
- Volume
- 144B
- Category
- Article
- ISSN
- 1552-4841
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The serotonin 2A (__5βHT2A__) receptor gene has been implicated in the pathogenesis of suicidal behavior by a genetic association between the 5βHT2A C102T silent polymorphism and suicidality in patients with major depression. However, a recent metaβanalysis failed to confirm this associ
Recent findings of an association between schizophrenia and a T102C polymorphism at the 5-HT 2a receptor gene (particularly with genotype 1-2 and 2-2 and allele 2) prompted us to investigate this marker in familial Irish schizophrenic patients, their relatives, and ethnically matched unrelated contr
Transgenic mice lacking a functional 5-HT 2c receptor gene are extremely susceptible to audiogenic seizures, suggesting that 5-HT 2c receptors mediate inhibition of neuronal network excitability. The present association study tested the hypothesis that a Cys23Ser substitution polymorphism within the