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Analysis of p16INK4A gene promoter in male germ-cell tumors: identification of a new point mutation

โœ Scribed by Joanna Fombonne; Mojgan Devouassoux-Shisheboran; Raymonde Bouvier; Jean-Pierre Droz; Mohamed Benahmed; Slavica Krantic

Book ID
113524259
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
394 KB
Volume
29
Category
Article
ISSN
0361-090X

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## Abstract Loss of p16^INK4a^ protein expression has frequently been related to DNA methylation in association with gene silencing. Although the methylation status of exon1ฮฑ for p16^INK4a^ involvement in various cancers has been extensively analyzed, it has been pointed out that some inconsistenci