A retrospective analysis was performed on all patients diagnosed with biopsyproven extragonadal germ cell tumors at the University of Virginia (Charlottesville, VA), The Medical University of South Carolina (Charleston, SC), the Bethesda Naval Hospital (Bethesda, MD), and The Medical College of Virg
Genetic analysis of the APAF1 gene in male germ cell tumors
β Scribed by Shashi Bala; Holt Oliver; Beatrice Renault; Kate Montgomery; Shipra Dutta; Pulivarthi Rao; Jane Houldsworth; Raju Kucherlapati; Xiaodong Wang; R.S.K. Chaganti; V.V.V.S. Murty
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 240 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1045-2257
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Autopsy findings are reviewed in 154 patients treated for germ cell tumors of the testis. OF the patients with apparently pure seminoma, 44% had autopsy evidence of nonseminomatous metastases. For all tumor types, the most common sites of distant metastasis were lung (89%), liver (73%), brain (31%),
Dysfunctional regulation and impaired expression of the FMR1 gene are responsible for the fragile X syndrome. We studied the transcriptional regulation of the normal gene and its aberrant regulation by mutation and methylation by analysis of in vivo protein/DNA contact at the promoter region [Schwem