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Analyses of Microsatellite Instability and the Transforming Growth Factor-β Receptor Type II Gene Mutation in Sporadic Human Gastrointestinal Cancer

✍ Scribed by Shuji Tomita; Hiroshi Miyazato; Osamu Tamai; Yoshihiro Muto; Takayoshi Toda


Book ID
114136955
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
326 KB
Volume
115
Category
Article
ISSN
0165-4608

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✍ Masayuki Ohue; Naohiro Tomita; Takushi Monden; Yasuo Miyoshi; Tadashi Ohnishi; H 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 517 KB

Forty-three sporadic gastric cancers were analyzed with regard to whether mutations of simple repeated sequences in the transforming growth factor fi type II receptor ( T p -I / ) gene are associated with microsatellite instability (MSI) and gastric carcinogenesis. In 12 ofthe 43 cancers (28%), MSI