Mutation Analysis of the Transforming Growth Factor β Type II Receptor in Sporadic Human Cancers of the Pancreas, Liver, and Breast
✍ Scribed by Francoise Vincent; Koichi Hagiwara; Yang Ke; Gary D. Stoner; Douglas J. Demetrick; William P. Bennett
- Book ID
- 115578610
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 164 KB
- Volume
- 223
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Forty-three sporadic gastric cancers were analyzed with regard to whether mutations of simple repeated sequences in the transforming growth factor fi type II receptor ( T p -I / ) gene are associated with microsatellite instability (MSI) and gastric carcinogenesis. In 12 ofthe 43 cancers (28%), MSI
To analyze transforming growth factor-b (TGF-b) response during MCF-7 cell progression, early passage (MCF-7E, õ200 passage) and late passage (MCF-7L, ú 500 passage) cells were compared. MCF-7E cells showed an IC 50 of Ç10 ng/ ml of TGF-b1, whereas MCF-7L cells were insensitive. MCF-7E cells contain