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Mutations of the Transforming Growth Factor-β Type II Receptor Gene and Genomic Instability in Hereditary Nonpolyposis Colorectal Cancer

✍ Scribed by S.L. Lu; Y. Akiyama; H. Nagasaki; K. Saitoh; Y. Yuasa


Book ID
115577562
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
370 KB
Volume
216
Category
Article
ISSN
0006-291X

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Mutations of the transforming growth fac
✍ Masayuki Ohue; Naohiro Tomita; Takushi Monden; Yasuo Miyoshi; Tadashi Ohnishi; H 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 517 KB

Forty-three sporadic gastric cancers were analyzed with regard to whether mutations of simple repeated sequences in the transforming growth factor fi type II receptor ( T p -I / ) gene are associated with microsatellite instability (MSI) and gastric carcinogenesis. In 12 ofthe 43 cancers (28%), MSI