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Analogues of d-glucosaminylphosphatidylinositol: synthesis of the glycosyl donors

โœ Scribed by Alexander P Dix; Charles N Borissow; Michael A.J Ferguson; John S Brimacombe

Book ID
104211444
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
100 KB
Volume
42
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Appropriately protected deoxy and other analogues of 2-azido-2-deoxy-D-glucopyranosyl fluoride have been synthesised preparatory to inclusion into analogues of the D-glucosaminylphosphatidylinositol 1.

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of 3โ€ฒ-, 4โ€ฒ- and 6โ€ฒ-deoxy and o
Synthesis of 3โ€ฒ-, 4โ€ฒ- and 6โ€ฒ-deoxy and other analogues of d-glucosaminylphosphatidylinositol
โœ Charles N Borissow; Terry K Smith; Michael A.J Ferguson; John S Brimacombe ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 80 KB

Deoxy and other analogues of D-glucosaminylphosphatidylinositol 1 have been synthesised and tested as substrates or inhibitors of a de-N-acetylase and mannosyltransferase (MT-1) involved in the biosynthesis of the glycosylphosphatidylinositol (GPI) membrane anchor of the parasite Trypanosoma brucei.