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Efficient Synthesis of α-Galactosyl Ceramide Analogues Using Glycosyl Iodide Donors

✍ Scribed by Du, Wenjun; Gervay-Hague, Jacquelyn


Book ID
127039657
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
56 KB
Volume
7
Category
Article
ISSN
1523-7060

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Predominant a-linked products can be generated in glycosylation involving galactosyl trichloroacetimidate donors with 2-naphthylmethyl (NAP) as the non-participating group at C-2 position. The above-mentioned donor was successfully utilized for the synthesis of a-galactosyl ceramide.