Developments concerning the fundamental role of nucleic acids in molecular t 'ology hove caused a dramatic increase of fundamental research into the chemistry of simple purine and pyrimidine'12 compounds. Even so, there ore many areas where our chemical knowledge is scant. This paper deals with one
An Unusual Base-catalyzed Cyclization
β Scribed by Schulenberg, John W.; Archer, S.
- Book ID
- 127051781
- Publisher
- American Chemical Society
- Year
- 1961
- Tongue
- English
- Weight
- 791 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Recently we prepared the enetrione, I, and demonstrated that intermolecular additions of nucleophiles to the double bond triggers a series of intramolecular condensations leading to products of relevance to steroids. 1 We now report an interesting isomerization of I, occasioned by its treatment wit
Li-h.? reduction of 14-Ethynyl-lfi -hydroxy-6,oxo-Sa-methyl-1,2,3,4, 6,7,8,8a octah J ronaphthalene 5 furnishes, in addition to reported products, the tricyclic compound 8. Metal\_ammonia reductions of the ketones 1 and 3 under controlled conditions are knownl to give the cyclopropanes 2 2nd 4 fesp