## Abstract ^14^C labeled 2‐amino‐7‐(3‐pyridylmethyl)‐4‐oxo‐3__H__,5__H__‐pyrrolo[3,2‐__d__]pyrimidine(6) was synthesized starting from methyl 3‐amino‐4‐(3‐pyridylmethyl)‐1__H__ ‐pyrrolo‐2‐carboxylate. This pyrrole on condensation with ^14^C labeled benzoylisothiocyanate followed by methylation gav
An improved synthesis of 9-(3-pyridylmethyl)-[2-14C]-9-deazaguanine
✍ Scribed by Cecil D. Kwong; Arthur J. Elliot; John A. Montgomery
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- French
- Weight
- 254 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-2135
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📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The syntheses of __N__^7^‐glycosylated 9‐deazaguanine **1a** as well as of its 9‐bromo and 9‐iodo derivatives **1b**,**c** are described. The regioselective 9‐halogenation with __N__‐bromosuccinimide (NBS) and __N__‐iodosuccinimide (NIS) was accomplished at the protected nucleobase **4a
A rapid, high yield (90-100%) method for the preparation of N-a~etoxy-N-acetyl-2-aminofluorene-9-~~C (N-AcO-AAF-9-14C) from N-hydroxy-N-a~etyl-2-aminofluorene-9-~~C (N-OH-AAF-9-14C) is described. The procedure conrists of the in situ formation of a quaternary amonium salt of N-OH-AAF-9-lq in a two-p