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An expeditious and efficient formal synthesis of (±)-aphidicolin

✍ Scribed by Masahiro Toyota; Youichi Nishikawa; Keiichiro Fukumoto


Book ID
108380169
Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
285 KB
Volume
35
Category
Article
ISSN
0040-4039

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📜 SIMILAR VOLUMES


Aphidicolin synthesis (II)—an expeditiou
✍ Masahiro Toyota; Youichi Nishikawa; Keiichiro Fukumoto 📂 Article 📅 1994 🏛 Elsevier Science 🌐 French ⚖ 941 KB

An expeditious and efftcient formal total synthesis of an antiviral and antitumor tetracyclic diterpene aphidicolin (1) has been achieved. An intramoleculat Heck reaction (74) and an intramolecular Diels-Aldex reaction (4+3) were utilii for the key steps of the sequence.