An expeditious and efftcient formal total synthesis of an antiviral and antitumor tetracyclic diterpene aphidicolin (1) has been achieved. An intramoleculat Heck reaction (74) and an intramolecular Diels-Aldex reaction (4+3) were utilii for the key steps of the sequence.
β¦ LIBER β¦
ChemInform Abstract: An Expeditious and Efficient Formal Synthesis of (.+-.)-Aphidicolin.
β Scribed by M. TOYOTA; Y. NISHIKAWA; K. FUKUMOTO
- Book ID
- 112020919
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0931-7597
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