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An expedient synthesis of (±)-γ-lycorane

✍ Scribed by Xuan Hoang-Cong; Béatrice Quiclet-Sire; Samir Z. Zard


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
143 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis


A short synthesis of (+)-'/-lycorane is described featuring a radical cascade whereby rings B and D are formed in one step.


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✍ Janine Cossy; Ludovic Tresnard; Domingo Gomez Pardo 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 331 KB 👁 1 views

Lycorane has been synthesized in ten steps from of (+)-γ-lycorane was achieved via an optically active unsaturated aldehyde intermediate. piperonylic alcohol. Two radical reactions were used successively to build the D and B rings. A formal synthesis [a] Laboratoire de Chimie Organique, associe ´au