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Amino Acid Intermediates: α-Amino-γ-lactones

✍ Scribed by Fillman, Jeanne; Albertson, Noel

Book ID
118067370
Publisher
American Chemical Society
Year
1948
Tongue
English
Weight
464 KB
Volume
70
Category
Article
ISSN
0002-7863

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A lacile slereoselcctive melhod Ior the synthesis of y-substituted, y-mnino acids from of amino acids was developed. The key step of the procedurc is complete reduction of Ihe keto functionality of ot-~unino acyl Meldruln's acid by sodium acetoxyborohydride. The resulting amino alkyl Meldrum's acid