The Rh-DuPHOS and Rh-BPE catalyzed hydrogenation of IS-substituted ¢x,[~,y,8-unsaturated amino acids establishes two contiguous stereogenic centers simultaneously. Both high regioselectivity and good to excellent enantioselectivity have been demonstrated in this process leading to I~-branched allyl
β,γ,-Unsaturated α-amino acid δ-lactones; precursors for polyhydroxy amino acids
✍ Scribed by Malcolm M. Campbell; Arthur J. Floyd; Terry Lewis; Mary F. Mahon; Ronald J. Ogilvie
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 174 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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