## Abstract A previous study of 18 primary or metastatic prostate cancers showed loss of genetic markers on chromosome 8; 10, or 16 in more than 50% of cases [Bergerheim USR et al. (1991) Genes Chromosom Cancer 3:215โ220]. The small size and infiltrative nature of primary prostatic tumors have hind
Allelic Imbalance of 8p Indicates Poor Survival in Gastric Cancer
โ Scribed by French, Amy J.; Petroni, Gina; Thibideau, Stephen N.; Smolkin, Mark; Bissonette, Eric; Roviello, Franco; Harper, Jeffrey C.; Koch, Benjamin R.; Anderson, Sarah A.; Hebbring, Scott J.; Powell, Steven M.
- Book ID
- 122166406
- Publisher
- American Society for Investigative Pathology
- Year
- 2004
- Tongue
- English
- Weight
- 269 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1525-1578
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In order t o detect regions of DNA containing tumor suppressor genes involved in the development of gastric cancer, we performed an allelotype study on 78 gastric adenocarcinomas from a population composed largely of Texan Hispanics and Anglos, two ethnic groups that have a ratio of incidence rates
Frequent allelic imbalance of polymorphic markers mapped to regions of the 7q, 8p, 16q, and 18q arms has been reported in prostate cancer. To better define the clinical significance of these genetic alterations, we undertook a retrospective analysis of systemic progression and survival in patients w