p53 accumulation and mutation are prognostic indicators of poor survival in human gastric carcinoma

Expression and mutation analyses of P53R

Expression and mutation analyses of P53R2, a newly identified p53 target for DNA repair in human gastric carcinoma

✍ Do-Sun Byun; Kwon-Seok Chae; Byung-Kyu Ryu; Min-Goo Lee; Sung-Gil Chi 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 247 KB

## Abstract __p53R2__, a recently identified putative tumor suppressor located at 8q23.1, encodes a protein with striking similarity to a small subunit of ribonucleotide reductase. __p53R2__ is directly induced by wild‐type p53 and involved in the p53 checkpoint for repair of damaged DNA, raising t