Allelic losses of tumor suppressor genes (TSGs), or the chromosomal regions harboring them, in tumor DNA may become useful postoperative prognostic indicators. To examine whether specific allelic losses might correlate with postoperative survival in a 5-year prospective follow-up, we tested tumors f
Correlation of allelic loss with poor postoperative survival in breast cancer
β Scribed by Mitsuru Emi; Yoshihito Utada; Masataka Yoshimoto; Takaaki Sato; Kaori Minobe; Satoshi Matsumoto; Futoshi Akiyama; Takuji Iwase; Shunsuke Haga; Tetsuro Kajiwara; Goi Sakamoto; Fujio Kasumi; Yusuke Nakamura
- Publisher
- Springer Japan
- Year
- 1999
- Tongue
- English
- Weight
- 597 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1340-6868
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We have previously reported a complete allelotype study of 86 primary breast carcinomas, in which each non-acrocentric chromosome arm was studied with at least one polymorphic DNA-marker for the presence of allelic imbalance (Al, allelic loss or allelic gain) in the tumor. Here we report the statist