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Algorithm for selection of optimized EPR distance restraints for de novo protein structure determination

✍ Scribed by Kelli Kazmier; Nathan S. Alexander; Jens Meiler; Hassane S. Mchaourab


Book ID
116697139
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
996 KB
Volume
173
Category
Article
ISSN
1047-8477

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The technique of two-dimensional nuclear magnetic resonance (2D-NMR) has recently assumed an active role in obtaining information on structures of polypeptides, small proteins, sugars, and DNA fragments in solution. In order to generate spatial structures from the atom-atom distance information obta