Design and selection of an intrabody library produced de-novo for the non-structural protein NSP5 of rotavirus

Total chemical synthesis, characterizati

Total chemical synthesis, characterization, and immunological properties of an MHC class I model using the TASP concept for protein de novo design

✍ G. Tuchscherer; C. Servis; G. Corradin; U. Blum; J. Rivier; M. Mutter 📂 Article 📅 1992 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 979 KB

## Abstract The design, total chemical synthesis, and immunological properties of a four‐__α__‐helix bundle template‐assembled synthetic protein (TASP) mimicking some of the structural features of the major histocompatibility complex (MHC) class I is described. In a first approach, the native seque