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Strategies for Selection from Protein Libraries Composed of de Novo Designed Secondary Structure Modules

✍ Scribed by Tomoaki Matsuura; Andreas Plückthun

Book ID: 111603093
Publisher: Springer Netherlands
Year: 2004
Tongue: English
Weight: 90 KB
Volume: 34
Category: Article
ISSN: 1573-0875
DOI: 10.1023/b:orig.0000009836.86519.eb

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## Abstract De novo designed peptide based super secondary structures are expected to provide scaffolds for the incorporation of functional sites as in proteins. Self‐association of peptide helices of similar screw sense, mediated by weak interactions, has been probed by the crystal structure deter