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‘Advanced’ generation lentiviruses as efficient vectors for cardiomyocyte gene transduction in vitro and in vivo

✍ Scribed by Bonci, D; Cittadini, A; Latronico, M V G; Borello, U; Aycock, J K; Drusco, A; Innocenzi, A; Follenzi, A; Lavitrano, M; Monti, M G

Book ID
110039238
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
263 KB
Volume
10
Category
Article
ISSN
0969-7128

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## Abstract ## Background Cationic lipids are at present very actively investigated for gene transfer studies and gene therapy applications. Basically, they rely on the formation of DNA/lipid aggregates via electrostatic interactions between their cationic headgroup and the negatively charged DNA.