Dextran–spermine polycation: an efficient nonviral vector for in vitro and in vivo gene transfection
✍ Scribed by Hosseinkhani, H; Azzam, T; Tabata, Y; Domb, A J
- Book ID
- 110039454
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 227 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0969-7128
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Background Cationic lipids are at present very actively investigated for gene transfer studies and gene therapy applications. Basically, they rely on the formation of DNA/lipid aggregates via electrostatic interactions between their cationic headgroup and the negatively charged DNA.
## Abstract ## Background Naked DNA and standard vectors have previously been used for gene delivery from implantable carrier matrices with great potential for gene therapeutic assistance of wound healing or tissue engineering. We have previously developed copolymer‐protected gene vectors which ar