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Octaarginine-modified chitosan as a nonviral gene delivery vector: properties and in vitro transfection efficiency

✍ Scribed by Xiaoli Zhao; Zhaoyang Li; Wenguang Liu; Wingmoon Lam; Peng Sun; Richard Y. T. Kao; Keith D. K. Luk; William W. Lu

Book ID: 106477621
Publisher: Springer Netherlands
Year: 2010
Tongue: English
Weight: 649 KB
Volume: 13
Category: Article
ISSN: 1388-0764
DOI: 10.1007/s11051-010-0067-3

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## Abstract ## Background Chitosans of high molecular weights have emerged as efficient nonviral gene delivery systems, but the properties and efficiency of well‐defined low molecular weight chitosans (<5 kDa) have not been studied. We therefore characterized DNA complexes of such low molecular we