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Strategies for improving the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo

✍ Scribed by Jayandharan, G R; Zhong, L; Li, B; Kachniarz, B; Srivastava, A

Book ID: 109855194
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 462 KB
Volume: 15
Category: Article
ISSN: 0969-7128
DOI: 10.1038/gt.2008.89

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## Abstract This study quantified and compared the transduction efficiencies of adenoviral (Ad), Arg‐Gly‐Asp (RGD)‐modified Ad, adeno‐associated viral serotype 2 (AAV2), and self‐complementary AAV2 (scAAV2) vectors within full‐thickness osteoarthritic (OA) and unaffected canine cartilage explants i