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Improvement of Transduction Efficiency of Recombinant Adeno-associated Virus Vector by Entrapment in Multilamellar Liposomes

✍ Scribed by Mizuno, Masaaki ;Yoshida, Jun

Book ID: 108581589
Publisher: Wiley (Blackwell Publishing)
Year: 1998
Tongue: English
Weight: 40 KB
Volume: 89
Category: Article
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1998.tb00570.x

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## Abstract ## Background Adeno‐associated virus (AAV) vectors have been shown to correct a variety of mutations in human cells by homologous recombination (HR) at high rates, which can overcome insertional mutagenesis and transgene silencing, two of the major hurdles in conventional gene addition