𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Addition of a methylcopper complex to acetylenes. Synthesis of trisubstituted olefins

✍ Scribed by Anthony Marfat; Paul R. McGuirk; Paul Helquist


Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
295 KB
Volume
19
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


Because of the widespread occurrence of the trisubstituted olefin unit in many classes of naturally occurring compounds, the synthesis of these olefins has received considerable


πŸ“œ SIMILAR VOLUMES


A new electrophilic addition to acetylen
✍ JosΓ© Barluenga; Miguel A RodrΓ­guez; JosΓ© M GonzΓ‘lez; Pedro J Campos; Gregorio As πŸ“‚ Article πŸ“… 1986 πŸ› Elsevier Science 🌐 French βš– 222 KB

Acetylenes react with bis(pyridine)iodo(I) tetrafluoroborate (1) in the presence of a wide variety of nucleophiles (F,Cl,Br,I,SCN,pyridine,OAc,anisole,H) to give 1,2iodofunctionalized olefins (4).

Determination of the configurations of t
✍ Paul R. McGuirk; Anthony Marfat; Paul Helquist πŸ“‚ Article πŸ“… 1978 πŸ› Elsevier Science 🌐 French βš– 266 KB

The addition of alkylcopper complexes to acetylenes (equation l), originally developed by Normantl and later investigated by Westmijze, 2 is a very useful approach to the synthesis of olefins. More recently we3 and others4 have modified this reaction through use of

The reaction of Ξ±,Ξ²-acetylenic ketones w
✍ George W. Kabalka; Su Yu; Nan-Sheng Li; Ute Lipprandt πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 187 KB

Allenoxyborinates, easily generated via the 1,4-addition of dicyclohexylborane to a,~acetylenic ketones, react in situ with excess starting ketone to afford stereodefined, functionalized trisubstituted olefins in high yields.