Acute promyelocytic leukemia: From clinic to molecular biology
β Scribed by Sai-Juan Chen; Zhen-Yi Wang; Zhu Chen
- Book ID
- 112212679
- Publisher
- AlphaMed Press
- Year
- 1995
- Tongue
- English
- Weight
- 910 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1066-5099
No coin nor oath required. For personal study only.
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The chromosome breakpoints of the acute promyelocytic leukemia (APL)-specific 15;17 translocation have recently been isolated. They are localized on a previously unknown gene, PML, on chromosome 15 and in the gene that encodes the alpha retinoic acid receptor (RART) on 17. The translocation, which i