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Activation of phospholipase D in CHO cells transfected with the human epidermal growth factor (EGF) receptor: Differential effects of protein kinase C activation and EGF

✍ Scribed by Marjorie Dunlop; Stella Clark


Book ID
119121751
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
618 KB
Volume
1220
Category
Article
ISSN
0167-4889

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The epidermal growth factor (EGF) receptor mediates the effects of both EGF and transforming growth factor alpha (TGFalpha). Recent data suggested that EGF acts as a partial agonist/antagonist in hepatocytes, TGFalpha exerting a larger maximal stimulation of DNA synthesis than EGF. To further study