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Compartmentalization of the Mitogen-Activated Protein Kinase (MAPK) in Hepatic Endosomes: Association with the Internalized Epidermal Growth Factor (EGF) Receptor

✍ Scribed by Robert Faure; Jean-François Gaulin; Sylvain Bourgoin; Suzanne Fortier


Book ID
118769132
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
217 KB
Volume
1
Category
Article
ISSN
1522-4724

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Response to transforming growth factor α
✍ G. Hege Thoresen; Tormod K. Guren; Dagny Sandnes; Matthew Peak; Loranne Agius; T 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 1 views

The epidermal growth factor (EGF) receptor mediates the effects of both EGF and transforming growth factor alpha (TGFalpha). Recent data suggested that EGF acts as a partial agonist/antagonist in hepatocytes, TGFalpha exerting a larger maximal stimulation of DNA synthesis than EGF. To further study