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Activation of p53/ATM-dependent DNA damage signaling pathway by shiga toxin in mammalian cells

✍ Scribed by Kaisar A. Talukder; Ishrat J. Azmi; K. Ahtesham Ahmed; M. Sabir Hossain; Yearul Kabir; Alejandro Cravioto; David A. Sack; Alam Nur-E-Kamal


Book ID
116748795
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
398 KB
Volume
52
Category
Article
ISSN
0882-4010

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## Abstract The phytochemical indole‐3‐carbinol (I3C), from cruciferous vegetables such as broccoli, has been shown to elicit a potent anti‐proliferative response in human breast cancer cell lines. Treatment of the immortalized human mammary epithelial cell line MCF10A with I3C induced a G1 cell cy