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ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage

✍ Scribed by Svetlana V. Khoronenkova; Irina I. Dianova; Nicola Ternette; Benedikt M. Kessler; Jason L. Parsons; Grigory L. Dianov


Book ID
116755153
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
934 KB
Volume
45
Category
Article
ISSN
1097-2765

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## Abstract The phytochemical indole‐3‐carbinol (I3C), from cruciferous vegetables such as broccoli, has been shown to elicit a potent anti‐proliferative response in human breast cancer cell lines. Treatment of the immortalized human mammary epithelial cell line MCF10A with I3C induced a G1 cell cy