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Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer

✍ Scribed by Attardi, Laura D; de Vries, Annemieke; Jacks, Tyler


Book ID
110068112
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
245 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract DNA damage is known to be an initiator of neuronal death in neurodegenerative conditions such as Parkinson's and Alzheimer's diseases. The mechanism linking DNA damage and neuronal death is not completely understood. Here, we delineate the mechanism by which neuronal death evoked by DNA