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Action of 7,12-Dimethylbenz(Alpha)Anthracene on the Mitotic Activity of Normal and Malignant Rat Fibroblasts in vitro

✍ Scribed by STARIKOVA, V. B.; VASILIEV, J. M.

Book ID
109621816
Publisher
Nature Publishing Group
Year
1962
Tongue
English
Weight
199 KB
Volume
195
Category
Article
ISSN
0028-0836

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The presence of ER in DMBA-tumors was demonstrated by the use of dextrancharcoal assay, sephadex chromatography, sucrose gradient sedimentation, and organ culture techniques. It was found that tumors have binding sites ranging from 10-" to 10-l' moles/mg protein, and a dissociation constant of ER 10